103898-11-9 Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate

ʻIke Laʻau Laʻau: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate hoʻohana mau ʻia ma ke ʻano he hui pale i ka ʻike ʻana i ka lāʻau.Hoʻopili ia me nā pūʻulu hana e like me nā hydroxyls a me nā amine i loko o nā molekala lāʻau, e hana ana i nā derivatives palekana tert-butoxycarbonyl (Boc).Hāʻawi kēia pale i ka synthesis paʻa a me ka hoʻomaʻemaʻe, a hiki ke hoʻoneʻe ʻia ka hui Boc ma lalo o nā kūlana kūpono e hōʻike i ka pūʻulu hana mua no nā hopena hou a i ʻole nā ​​​​haʻawina hana biological.No laila, loaʻa iā ia nā noi i ka synthesis lāʻau lapaʻau, hoʻololi lāʻau, a me ka hoʻokuʻu ʻana i ka lāʻau.

Peptide Synthesis: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate loaʻa hoʻi ka hoʻohana ʻana ma ke ʻano he loulou i ka peptide synthesis.Hiki iā ia ke hana me ka hui carboxyl o nā waikawa amino, e hana ana i nā paʻa amide paʻa e hoʻohui i ʻelua a ʻoi aku ka nui o nā waikawa amino, e hana ana i nā kaulahao peptide me nā kaʻina a me nā hale kikoʻī.Hoʻohana nui ʻia kēia linker i ka solid-phase peptide synthesis, wai-phase peptide synthesis, a me nā ʻano hana ʻē aʻe.

Noiʻi Biochemical: Ma muli o kona ʻano biodegradable, hoʻohana ʻia ʻo Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate ma ke ʻano he mea hana i ka noiʻi biochemical.No ka laʻana, hiki ke hoʻohana ʻia ma ke ʻano he loulou i ka synthesis o nā antibody-drug conjugates (ADCs), e hoʻopili ana i nā lāʻau lapaʻau i nā antibodies no ka lawe ʻana a me ka hoʻokuʻu ʻana.Hoʻohui ʻia, hiki ke hoʻohana ʻia e aʻo i ka protein-protein a me ka protein-ligand interactions, a me ka localization protein a me ka hana i loko o nā cell.