NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
ola mālama
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
N-ALPHA-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-N-EPSILON-BOC-L-LYSINE;
N-ALPHA-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE;
N-ALPHA-(4-4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-N-EPSILON-TERT-BUTYLOXYCARBONYL-L-LYSINE;
L-Lysine,N2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N6-[(1,1-dimethylethoxy)carbonyl]-;
(2S)-6-{[(tert-butoxy)carbonyl]amino}-2-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}hexanoicacid;
N-α-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl]-N-ε-(t-butoxycarbonyl)-L-lysine
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
ʻO ka Biochemistry a me ka Hoʻomohala Lapaʻau: Ma ke ʻano he derivative o kahi amino acid me kahi ʻano kemika kikoʻī, hiki ke loaʻa iā DDE-L-LYS(BOC)-OH ka hoʻohana ma ke ʻano he mea waena i ka synthesis o nā peptides a i ʻole nā protein no ka hoʻomākaukau ʻana i nā lāʻau lapaʻau a i ʻole nā molekole bioactive me nā hana ola kino.
Peptide Synthesis: Ma ka peptide synthesis, hiki i ka DDE-L-LYS (BOC) -OH ke lilo i hale kūkulu hale no ka hui ʻana o nā peptides me nā ʻano kikoʻī a me nā hana ma o ka hoʻopili ʻana me nā amino acids a i ʻole nā ʻāpana peptide.
ʻEpekema Mea Hana: Ma muli o kāna mau waiwai kemika kū hoʻokahi, hiki i ka DDE-L-LYS(BOC)-OH ke hoʻohana i ka ʻepekema waiwai, e like me ka hoʻomākaukau ʻana i nā mea hoʻohui ponoʻī, nā mea biocompatible, a i ʻole nā pale bioactive.
Boc-Lys(Ivdde)-OH | Fmoc-Lys(ivdde)-OH | Fmoc-L-Lys(dde)-OH | Boc-L-Lys(Boc)-OSu |
Boc-Lys(Boc)-OH | Boc-D-Lys(Boc)-OH | Boc-D-Lys(Boc)-OH | Fmoc-Lys(Boc)-OH |
Cbz-Lys(BOC)-ome | Cbz-L-Lys(BOC)-OH | L-Lys(Boc) |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.