NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Ola ola
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
BOC-N-ME-DL-PHG-OH;
BOC-N-METHYL-DL-PHENYLGLYCINE;
N-Boc-a-(MethylaMino)benzeneaceticacid;
Boc-N-methyl-DL-phenylglycine≥99%(HPLC);
Benzeneaceticacid,α-[[(1,1-dimethylethoxy)carbonyl]methylamino]-;
2-{[(tert-butoxy)carbonyl](methyl)amino}-2-phenylaceticacid;
N-Boc-N-methyl-DL-phenylglycine;
2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-2-phenylaceticacid
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
Ka noiʻi biochemical:
Ma ka peptide synthesis, hiki i ka Boc-N-Me-DL-Phg-OH ke lawelawe ma ke ʻano he hale kūkulu koʻikoʻi no ka hoʻohui ʻana i nā kaulahao peptide me nā kaʻina amino acid kikoʻī.
Ma muli o kāna mau hiʻohiʻona, hiki ke hoʻohana ʻia e aʻo i nā hoʻololi a me nā pilina o nā protein a i ʻole nā peptides, e hoʻomaopopo i ka hopena o kēia mau loli i nā hana olaola a i ʻole ka pilina me nā molekala ʻē aʻe.
ʻIke lāʻau lapaʻau:
Hiki ke hoʻohana ʻia ʻo Boc-N-Me-DL-Phg-OH ma ke ʻano he mea hoʻomaka a waena paha i ka ʻike ʻana i ka lāʻau lapaʻau, e pane ana me nā ʻāpana lāʻau lapaʻau ʻē aʻe a i ʻole nā moleke olaolaola e hoʻohui i nā lāʻau lapaʻau peptide me nā hopena therapeutic kikoʻī.
Hiki ke hoʻohana ʻia i ka hoʻāʻo ʻana i ka lāʻau lapaʻau a me nā hoʻāʻo hana biological e loiloi i ka hana o nā ʻano peptide like ʻole a i ʻole nā moho lāʻau.
ʻoihana lāʻau lapaʻau:
I ka ʻoihana lāʻau lapaʻau, hiki i ka Boc-N-Me-DL-Phg-OH ke lawelawe ma ke ʻano he mea maka a i ʻole waena no ka hana ʻana i nā lāʻau peptide therapeutically active.
Ma o ka condensation reactions me nā amino acids a i ʻole nā ʻāpana lāʻau lapaʻau, hiki ke hoʻohana ʻia e synthesize i nā lāʻau peptide me nā hana kūlohelohe kūikawā, e like me nā antibiotics, hormones, enzyme inhibitors, a me nā mea ʻē aʻe.
Boc-N-Me-L-Phg-OH | Fmoc-N-Me-L-Phg-OH | Boc-N-Me-D-Phg-OH | Fmoc-N-Me-D-Phg-OH |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.