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340-90-9 N-Pht-Glu

340-90-9 N-Pht-Glu

ʻO ka wehewehe pōkole:

Ka nana aku ʻO ka pauka keʻokeʻo keʻokeʻo
MF C13H11NO6
MW 277.23
Maemae 98+


Huahana Huahana

Kūlana halihali
Hiki i ka wela maʻamau

Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai

Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela

Ola ola
Ma kahi o 2 makahiki

Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)

palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20                      

E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.

No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.

D-Lys(tfa)-NCA (2)

Nā huaʻōlelo like

(2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentanedioicacid;

n-phthalyl-l-glutamicacid;

N-PHTHALIMIDEL-GLUTAMINCACID;

N-PHTHALOYL-L-GLUTAMICACID;

PTHALYL-L-GLUTAMICACID;

PHTHALOYL-L-GLUTAMICACID;

PHT-GLU-OH;

PHGA

Hoʻopili i loko

Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.

Hoʻopili i loko 2
Hoʻopili i loko 1
Hoʻopili i loko 3

kāʻei waho

1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.

Hoʻopili waho 3
Hoʻopili waho 2
Hoʻopili waho 1

Nā noi

Hiki ke hoʻohana ʻia ka PTHHALYL-L-GLUTAMIC ACID e hana (R)-(+)-THALIDOMIDE.He glutamic acid derivative me ka hopena therapeutic ʻole i ka maʻi lepera, a hoʻohana pū ʻia me nā lāʻau antileprosy e hōʻemi i ka hopena o ka maʻi lepera a mālama i nā ʻano ʻano like ʻole o ka maʻi lepera, e like me ka hoʻonui ʻia o nā lymph nodes, erythema nodosum, fever, arthralgia a me neuralgia me ka maikaʻi maikaʻi. .
Ua ʻokoʻa loa nā hopena immunomodulatory o ka thalidomide e like me nā kūlana hoʻokolohua, me nā hopena kū'ē i kekahi manawa.ʻO nā hopena ma nā lymphocytes ka emi ʻana o nā pūnaewele CD4+ a me ka hoʻoulu ʻana o nā pūnaewele CD8+, e hopena i ka emi ʻana o ka lakene CD48.
Eia kekahi, ʻike ʻia ka thalidomide i ka hoʻololi ʻana mai kahi Th1 a i kahi pane Th2.
Ua hana ʻo Cyclosporine a me thalidomide ma nā ʻano ʻelua o T lymphocytes, Th1 a me Th2, a ua ʻike ʻia ʻo Thd e hoʻoulu a hoʻonui i ka synthesis o IL-4 a me IL-5, e kāohi i ka synthesis o interferon gamma (IFN-γ) e phytohemagglutinin-hoʻoulu kanaka. nā monocytes koko peripheral, a hoʻemi i nā kiʻekiʻe o TNF-α, IL-6, a me IL-10 mRNA, me ka hopena ʻole o ka pae IL-12 a me IFN-γ mRNA ʻaʻohe hopena.

huahana pili

HL-Glu-OH HD-Glu-OH DL-Glu-OH Boc-L-Glu-OH
Boc-D-Glu-OH Boc-Glu(trt)-OH Fmoc-L-Glu-OH Fmoc-D-Glu-OH
Cbz-L-Glu-OH Cbz-D-Glu-OH Cbz-L-Glu-Otbu Cbz-L-Glu(Oet)-OH

No ke aha e koho ai iā mākou

1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, ​​​​hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.


  • Mua:
  • Aʻe:

  • E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou