NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Ola ola
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
ʻO N-Me-D-Phe, a i ʻole N-methyl-D-phenylalanine, he mea hoʻoheheʻe amino acid maoli ʻole.ʻOiai ʻaʻole laha loa kāna mau noi e like me kekahi mau amino acids maʻamau, paʻa mau ia i ke koʻikoʻi a me ka waiwai ma nā kahua kikoʻī a me nā noi.
Hiki i ka N-Me-D-Phe ke lawelawe ma ke ʻano he ʻāpana i ka synthesis o peptides a i ʻole peptide mimics, i hoʻohana ʻia e aʻo i ka pilina ma waena o nā protein a me nā peptides.Ma muli o kona ʻano chiral (D-type, ʻo ia ke kiʻi aniani o nā ʻakika amino L-ʻano maoli), hiki ke hōʻike i nā hana olaola like ʻole a i ʻole nā ʻano hoʻopaʻa i hoʻohālikelike ʻia me nā waikawa amino L-type maoli.No laila, hiki ke hoʻohana ʻia i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a i ʻole nā molekole bioactive me nā hana ʻokoʻa o ka hana a i ʻole ke koho kiʻekiʻe.
I loko o ka biotechnology a me ka biology molecular, hiki ke hoʻohana ʻia ʻo N-Me-D-Phe i ka synthesis o nā peptides a i ʻole nā protein me nā hana kikoʻī, e like me nā enzymes, receptors, a i ʻole nā molekele hōʻailona.Hiki i kēia mau mole ke hana koʻikoʻi i ka maʻi maʻi a me ka mālama ʻana, ka nānā ʻana i ka lāʻau lapaʻau, a me nā haʻawina hana protein.
Eia kekahi, ʻike paha ʻo N-Me-D-Phe i nā noi i ka ʻepekema waiwai, e like me ka synthesis o nā mea hoʻohui ponoʻī, nanomaterials, a i ʻole nā mea biocompatible.Ma ka launa pū ʻana me nā molekala ʻē aʻe, hiki iā ia ke hoʻololi i nā waiwai kino a me nā kemika o nā mea, e alakaʻi ana i ka hoʻomohala ʻana i nā mea hou me nā hana kikoʻī.
Boc-N-Me-L-Phe-OH | ZN-Me-L-Phe-OH | Fmoc-N-Me-L-Phe-OH | BOC-N-Me-D-Phe-OH |
FMOC-N-Me-D-Phe-OH | Boc-N-Me-L-Phe-OH.DCHA | Boc-DN-Me-Phe.DCHA | Fmoc-N-Me-D-Leu-OH |
Boc-N-Me-DL-Phe-OH |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.