NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
ola mālama
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
Fmoc-Arg(Pbf)-Gly-OH;
(9H-Fluoren-9-yl)MethOxy]CarbonylArg(Pbf)-Gly-OH;
2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-{N'-[(2,2,4,6,7-pentamethyl-2, 3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanamido]aceticacid;
Glycine,N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl ]-L-ornithyl-
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
Peptide Synthesis: ʻO kēia kekahi o nā noi mua o Fmoc-Arg (Pbf) -Gly-OH.I ka peptide synthesis, lawelawe ia ma ke ʻano he hale kūkulu hale hiki ke hoʻohui ʻia me nā waikawa amino ʻē aʻe e hana i nā kaulahao peptide me nā ʻano kikoʻī a me nā hana.
ʻIke Laʻau Laʻau: Ma muli o kāna ʻano kemika kūʻokoʻa a me nā hana olaola hiki ke loaʻa, Fmoc-Arg(Pbf)-Gly-OH paʻa ka waiwai nui i ka ʻike ʻana i ka lāʻau.Hiki ke lilo i mea koʻikoʻi i ka synthesizing i nā lāʻau lapaʻau hou, ʻoi aku ka peptide-based therapeutics.
Ka noiʻi biochemical: Ma ka noiʻi biochemical, hiki i ka Fmoc-Arg (Pbf) -Gly-OH ke lilo i mea hana waiwai no ke aʻo ʻana i ka pilina o ka protein-protein, nā hana enzyme, nā hale protein, a me nā wahi ʻē aʻe.Ma ka hoʻokomo ʻana iā ia i loko o nā kaʻina peptide, hiki i nā mea noiʻi ke ʻimi i kona hiki ke hoʻopaʻa ʻia a me nā hana olaola me nā molekole target.
Cbz-Phe-Arg-OH | HL-Arg-OH | HD-Arg-OH | L-Arg(Pbf)-OH |
Boc-D-Arg(Pbf) | Boc-Arg(Pbf)-OH | Fmoc-L-Arg-OH | Fmoc-D-Arg-OH |
Fmoc-D-Arg(Pbf)-OH | Cbz-L-Arg(Pbf)-OH | Cbz-D-Arg(pbf).CHA |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.