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67424-93-5 Cbz-D-His-OH

67424-93-5 Cbz-D-His-OH

ʻO ka wehewehe pōkole:

Ka nana aku ʻO ka pauka keʻokeʻo keʻokeʻo
MF C14H15N3O4
MW 289.29
Maemae 98+


Huahana Huahana

Kūlana halihali
Hiki i ka wela maʻamau

Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai

Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela

ola mālama
Ma kahi o 2 makahiki

Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)

palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20                      

E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.

No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.

D-Lys(tfa)-NCA (2)

Nā huaʻōlelo like

Nalpha-Cbz-D-histidine

ZD-His-OH;

Cbz-D-histidine;

(R)-2-(Benzyloxycarbonylamino)-3-(1H-imidazol-4-yl)propionicacid;

(R)-α-[[(Benzyloxy)carbonyl]amino]-1H-imidazole-4-propanoicacid;

Nα-(Benzyloxycarbonyl)-D-histidine;

Nα-Carbobenzoxy-D-histidine;

N(ALPHA)-CBZ-D-HISTIDINE

Hoʻopili i loko

Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.

Hoʻopili i loko 2
Hoʻopili i loko 1
Hoʻopili i loko 3

kāʻei waho

1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.

Hoʻopili waho 3
Hoʻopili waho 2
Hoʻopili waho 1

Nā noi

Puʻupuʻu Palekana i ka Synthesis Peptide: Ma ka peptide synthesis, hoʻohana pinepine ʻia ka hui Cbz (benzyloxycarbonyl) ma ke ʻano he pūʻulu pale N-terminal no nā waikawa amino.Mālama maikaʻi ia i ka pūʻulu amino mai nā hopena i makemake ʻole ʻia i ka wā o ka synthesis.Ma ka hoʻokomo ʻana iā Cbz-D-His-OH, hiki i nā mea noiʻi ke hoʻokō pololei i ka histidine i ka wā o ka synthesis o nā peptides kikoʻī, e alakaʻi ana i nā kaʻina peptide i makemake ʻia.

Hoʻolālā a me ka hoʻomohala ʻana i ka lāʻau lapaʻau: ʻO Histidine kahi waikawa amino koʻikoʻi me nā hana physiological he nui i loko o nā meaola.ʻO ka hoʻololi ʻana i ka histidine, e like me ka hoʻokomo ʻana i ka hui Cbz, hiki ke hoʻololi i kāna mau mea kemika a me nā hana olaola, hiki ke alakaʻi i ka hoʻolālā ʻana i nā moho lāʻau lapaʻau hou.ʻO ke ʻano kikoʻī a me nā waiwai o Cbz-D-His-OH e hoʻolilo iā ia i mole mole moho i ka hoʻolālā lāʻau.

Ka noiʻi biochemical: Cbz-D-His-OH lawelawe ma ke ʻano he mea hana pono mole i ka noiʻi biochemical.No ka laʻana, hiki ke hoʻohana ʻia no ka noiʻi ʻana i ka pilina ma waena o nā protein a me ka histidine a i ʻole e hoʻomākaukau i nā ʻimi noiʻi olaola pili i ka histidine a me nā lepili.Hāʻawi kēia mau haʻawina i ka ʻike hohonu o nā mīkini paʻakikī e like me ka metabolism a me ka hoʻololi ʻana i nā hōʻailona i loko o nā meaola.

Intermediate in Organic Synthesis: Ma ke kahua o ka organic synthesis, Cbz-D-His-OH hiki ke lawelawe ma ke ano he kuwaena no ke kukulu ana i na mole mole.Ma ka hana ʻana me nā pūhui ʻē aʻe, hiki iā ia ke hana i ka synthesis o nā molekala organik me nā hale a me nā hana kikoʻī, hiki ke loaʻa nā noi kūpono i nā wahi e like me nā mea hou a me nā catalysts.

huahana pili

D-Kona(trt)-OH Boc-L-His-OH Fmoc-L-His-OH FMOC-D-Kona(Mmt)-OH

No ke aha e koho ai iā mākou

1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, ​​​​hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.


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