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84758-55-4 Boc-Aib-Ome

84758-55-4 Boc-Aib-Ome

ʻO ka wehewehe pōkole:

Ka nana aku Pauda keʻokeʻo
MF C10H19NO4
MW 217.26
Maemae 98+


Huahana Huahana

Kūlana halihali
Hiki i ka wela maʻamau

Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai

Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela

Ola ola
Ma kahi o 2 makahiki

Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)

palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20                      

E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.

No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.

D-Lys(tfa)-NCA (2)

Nā huaʻōlelo like

methyl 2-tert-butoxycarbonylamino-2-methylpropanoate;
methyl 2-aminobutoxycarbonyl-2-methylpropanoate;
N-tert-butoxycarbonyl-α-methylalanine methyl ester;
methyl 2-(tert-butoxycarbonylamino) -2-methylpropanoate;
N-(tert-butoxycarbonyl)-α-methylalanine methyl ester;
methyl N-(tert-butoxycarbonyl)-2-methyl-alaninate;

Hoʻopili i loko

Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.E hōʻoia mākou i ka pūʻolo me ʻoe ma mua a ma hope o ka puka ʻana mai o nā huahana a hoʻouna iā ʻoe i nā kiʻi.

Hoʻopili i loko 2
Hoʻopili i loko 1
Hoʻopili i loko 3

kāʻei waho

He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.

Hoʻopili waho 3
Hoʻopili waho 2
Hoʻopili waho 1

Nā noi

ʻO ka Peptide Synthesis: lawelawe ʻo Boc-Aib-Ome ma ke ʻano he hale kūkulu hale i ka synthesis peptide solid-phase.Hiki ke hoʻohui ʻia i loko o nā kaulahao peptide e hoʻolauna i nā kaʻina amino acid kikoʻī.Hiki i ka hui pale Boc ke hoʻopaʻa ʻia i ka hoʻopili ʻana, e hōʻoia ana i ka hui pololei ʻana o nā peptides.Ke pau ka peptide synthesis, hiki ke wehe ʻia ka hui Boc e hōʻike i ka hana amino no nā hoʻololi hou a i ʻole conjugation.

Loaʻa i ka lāʻau lapaʻau: ʻike ʻo Boc-Aib-Ome i nā noi i ka hoʻolālā ʻana i nā lāʻau lapaʻau peptide hou.Ma ka hoʻokomo ʻana i kēia derivative amino acid i loko o nā kaʻina peptide, hiki i nā mea noiʻi ke ʻimi i nā mea lapaʻau kūpono me nā hana biological kūʻokoʻa.Hāʻawi ka hui pale Boc i ka paʻa i ka wā o ka hana synthetic, hiki ke hoʻomākaukau i nā conjugates peptide me nā waiwai pharmacokinetic i hoʻomaikaʻi ʻia.

Bioconjugation: Hiki ke hoʻohana ʻia ʻo Boc-Aib-Ome i nā hopena bioconjugation e hoʻopili i nā peptides a i ʻole nā ​​​​protein i nā molekala olaola ʻē aʻe.Hiki i ka hana methyl ester ke hoʻopili covalent i nā molekole like ʻole, e like me nā antibodies, carbohydrates, a i ʻole nā ​​​​peptides ʻē aʻe.Hāʻawi kēia i ka hana ʻana i nā ʻōnaehana hoʻopuka i manaʻo ʻia, biosensors, a i ʻole nā ​​​​conjugates bioactive ʻē aʻe me ka hana i hoʻonui ʻia.

Nā Haʻawina Biochemical: Hiki ke hoʻohana ʻia ʻo Boc-Aib-Ome ma ke ʻano he mea hana i nā noiʻi biochemical e noiʻi ai i ka pilina protein-protein, enzyme kinetics, a i ʻole substrate specificity.Ma ka hoʻokomo ʻana i kēia derivative amino acid i loko o nā peptides i hoʻohana ʻia ma ke ʻano he probes a i ʻole inhibitors, hiki i nā mea noiʻi ke loaʻa nā ʻike i nā hana o nā kaʻina hana olaola.

huahana pili

Aib Boc-Tyr(Akā).Aib 2-Aib-Ome.Hcl
2-Aib-Ome.Hcl 2-Aib-Ome.Hcl L-Aib-Oet.Hcl
Boc-Aib-OH Boc-Aib-OH Boc-Aib-OH
Boc-aib-Ome Fmoc-Aib-OH Fmoc-Aib-OH
Fmoc-Aib-OH Fmoc-Aib-OH Fmoc-Aib-OH
Fmoc-Aib-OH Z-Aib-OH Cbz-Aib-Otbu

Kiekie

1. Hāʻawi mākou i ka hana maʻamau i nā huahana āu e pono ai.
2. Hiki ke hāʻawi ʻia ke kumukūʻai kiʻekiʻe & hoʻokūkū.
3.We hoʻohiki i kahi papa piha o ka lawelawe ukali no ʻoe.
4. Hiki ke hā'awi 'ia ka nīnau nīnau mea kū'ai a me nā palapala 'ike loea inā noi ma hope o ka hālāwai 'ana i kekahi huina.
5. Nui ma hope o ke kūʻai aku ʻana a i ʻole ka hōʻoia ʻana: E hoʻoponopono koke ʻia kāu nīnau i ka hiki.
6. E hoʻokuʻu aku i nā huahana hoʻokūkū a hoʻokuʻu aku iā lākou i waho i nā mea nui i kēlā me kēia makahiki.
7.Free hāpana hāʻawi ʻia e nānā i ka maikaʻi ma mua o kekahi uku.


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