NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Ola ola
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
BOC-N-METHYL-D-PHENYLALANINE;
BOC-N-ME-D-PHENYLALANINE;
BOC-N-ME-D-PHE-OH;
BOC-N-ALPHA-METHYL-D-PHENYLALANINE;
BOC-D-MEPHE-OH;
N-ALPHA-T-BOC-N-ALPHA-METHYL-D-PHENYLALANINE;
N-ALPHA-T-BUTOXYCARBONYL-N-ALPHA-METHYL-D-PHENYLALANINE;
N-ALPHA-T-BUTOXYCARBONYL-N-METHYL-D-PHENYLALANINE
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
ʻO ka Peptide Synthesis: ʻO BOC-N-Me-D-Phe-OH kahi mea koʻikoʻi i ka synthesis peptide solid-phase.Ma muli o kona palekana tert-butoxycarbonyl (BOC) ma ka N-terminus a me ka pale N-methyl ma ke kaulahao ʻaoʻao, hāʻawi ia i ka paʻa a me ka koho i ka wā o ka peptide elongation kaʻina.Hāʻawi kēia i nā mea noiʻi e synthesize i nā peptides me nā kaʻina a me nā hoʻolālā pololei.
Hoʻolālā a me ka hoʻomohala ʻana i ka lāʻau: BOC-N-Me-D-Phe-OH he hana koʻikoʻi i ka hoʻolālā a me ka hoʻomohala ʻana i ka lāʻau.Hiki ke hoʻohui ʻia i loko o nā moho lāʻau lapaʻau ma ke ʻano he hoʻololi kemika kūikawā, e manaʻo ana e hoʻonui i kā lākou hana, kūpaʻa, a i ʻole nā mea pharmacokinetic.Hoʻohui ʻia, hiki ke hoʻohana ʻia kēia pūhui e aʻo i nā ʻano hana pilina ma waena o nā lāʻau lapaʻau a me nā biomolecules.
ʻEnekinia Protein: Ma ka ʻenekinia protein, hiki ke hoʻohana ʻia ʻo BOC-N-Me-D-Phe-OH e hoʻololi a ʻenekinia paha i ke ʻano a me ka hana o nā protein.Ma ka hoʻokomo ʻana iā ia i nā kūlana kikoʻī i loko o kahi protein, hiki iā ia ke hoʻololi i ke kūpaʻa, ka hana, ka pilina, a i ʻole nā mea biophysical ʻē aʻe o ka protein.Kōkua kēia i ka hana ʻana i nā protein hou me nā hana i makemake ʻia.
Biological Probes: Hiki ke hoʻohana ʻia ka pūhui ma ke ʻano he noiʻi olaola e aʻo ai i ke ʻano a me ka hana o nā biomolecules e like me nā protein, nā enzymes, a i ʻole nā mea hoʻokipa.Ma ka hoʻohui ʻana iā ia me nā dyes fluorescent a i ʻole nā lepili ʻē aʻe, hiki ke hoʻohana ʻia ʻo BOC-N-Me-D-Phe-OH no ka nānā ʻana a ʻike paha i ka hāʻawi ʻana a me ka hoʻoikaika ʻana o nā biomolecules i loko o nā cell a i ʻole nāʻiʻo.
Boc-N-Me-L-Phe-OH | ZN-Me-L-Phe-OH | Fmoc-N-Me-L-Phe-OH | N-Me-D-Phe |
FMOC-N-Me-D-Phe-OH | Boc-N-Me-L-Phe-OH.DCHA | Boc-DN-Me-Phe.DCHA | Fmoc-N-Me-D-Leu-OH |
Boc-N-Me-DL-Phe-OH | HN-Me-L-Phe-OH | HN-Me-L-Phe.Hcl |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.