NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
ola mālama
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
DN-Me-val / N-Me-D-val;
N-Methyl-D-valine;
(2R) -3-methyl-2-(methylamino)butanoic acid;
(R)-3-Methyl-2-(methylamino)butanoic acid;
HDN-Me-Val-OH;
N-Me-D-Val;
D-Valine, N-methyl-;
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
Ke noiʻi ʻana i ka biochemical a me ka molecular biology:
Hoʻohana pinepine ʻia ʻo N-Me-D-Val ma ke ʻano he ʻimi a hōʻailona paha i ka noiʻi biochemical a me ka molecular biology e aʻo ai i ke ʻano o ka protein a me ka hana, nā pilina enzyme-substrate, a me nā kaʻina hana ola ʻē aʻe.
Hiki i kāna hoʻololi methylated kūʻokoʻa ke hoʻololi a hoʻololi paha i nā pilina ma waena o nā molekala olaola, e hāʻawi ana i nā mea noiʻi me nā ʻike hou i nā kaʻina hana olaola.
Hoʻolālā a me ka hoʻomohala ʻana i ka lāʻau lapaʻau:
Loaʻa iā N-Me-D-Val nā noi i ka hoʻolālā lāʻau.Hiki ke lawelawe ma ke ʻano he hui alakaʻi no ka hoʻomohala ʻana i nā lāʻau hou a i ʻole no ka hoʻonui ʻana i ka pono o nā lāʻau i loaʻa.
Ma o ke aʻo ʻana i kāna ʻano hana a me kāna hana olaola, hiki i nā ʻepekema ke ʻimi i kona hiki ke mālama i kekahi mau maʻi a i ʻole nā kūlana.
ʻEpekema Synthetic a me Material Science:
Ma ke ʻano he kumu waiwai nui a i ʻole waena i ka synthesis organik, hiki ke hoʻohana ʻia ʻo N-Me-D-Val e synthesize i nā pūhui organik a i ʻole nā mea polymeric me nā hana kikoʻī.
ʻO kāna mau waiwai kemika kūikawā hiki ke hoʻohana ʻia i ka hoʻololi ʻana i nā mea, ka polymer synthesis, a me ka hoʻomākaukau ʻana i nā mea hana.
ʻOihana meaʻai a me ka ʻoihana meaʻai:
ʻOiai e kaupalena ʻia nā noi pololei o N-Me-D-Val i nā meaʻai a me nā mea hoʻohui meaʻai, ʻo kāna waiwai noiʻi i ka ʻepekema meaʻai a me ka noiʻi ʻepekema meaʻai he mea nui.
ʻO ke aʻo ʻana i kona hopena i ka metabolism a me ka absorption meaʻai i loko o nā meaola hiki ke hāʻawi i nā hoʻolālā hou no ka hoʻonui ʻana i ka meaʻai a i ʻole ka hoʻomaikaʻi ʻana i ka hana i ka ʻoihana meaʻai.
L-Val-OH | DL-Val | HD-Val-OH | N-Me-L-Val-OH |
N-Me-L-Val.HCl | Cbz-N-Me-D-Val-OH | N-Me-D-Val-OH·HCl | N-Me-L-Val-Ome.HCl |
N-Me-D-Val-Ome.HCl | N-Me-Val-Obzl.HCl | N-Me-D-Val-Obzl.HCl | N-Me-Val-Obzl.Tos |
Boc-N-Me-Val-OH | Boc-N-Me-D-Val-OH | Fmoc-N-Me-Val-OH | Fmoc-N-Me-DL-Val-OH |
Fmoc-N-Me-D-Val-OH | Cbz-N-Me-L-Val-OH |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.