NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
ola mālama
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
BOC-N-ALPHA-METHYL-D-VALINE;
D-Valine,N-[(1,1-diMethylethoxy)carbonyl]-N-Methyl-;
BOC-N-METHYL-D-VALINE;
BOC-N-ME-D-VALINE;
BOC-N-ME-D-VAL-OH;
BOC-D-MEVAL-OH;
N-ALPHA-T-BOC-N-ALPHA-METHYL-D-VALINE;
N-ALPHA-TERT-BUTYLOXYCARBONYL-N-ALPHA-METHYL-D-VALINE
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
Peptide Synthesis: Ma ke kahua o ka peptide synthesis, lawelawe ʻo Boc-N-Me-D-Val-OH i koena amino acid koʻikoʻi hiki ke hoʻokomo ʻia i loko o nā kaulahao peptide.ʻO kona kūpaʻa maikaʻi a me ka solubility e hāʻawi i ka peptide synthesis ʻoi aku ka maikaʻi, e hopena i nā peptides target maʻemaʻe kiʻekiʻe.
Noiʻi Biochemical: Ma ka biochemistry, lawelawe ʻo Boc-N-Me-D-Val-OH ma ke ʻano he mea noiʻi noiʻi e ʻimi ai i ka pilina hana-hana o nā peptides a me nā protein.Ma ka hoʻokomo ʻana iā ia i loko o nā kaulahao peptide, hiki i nā mea noiʻi ke loaʻa ka ʻike hohonu o ka pilina intermolecular a me nā ʻano hoʻoponopono o nā kaʻina biological.
Hoʻomohala Lapaʻau: Ua loaʻa i nā lāʻau lapaʻau peptide ka nānā nui ʻana ma muli o ko lākou kikoʻī kiʻekiʻe a me ka haʻahaʻa haʻahaʻa.ʻO Boc-N-Me-D-Val-OH, ma ke ʻano he kī nui i ka peptide synthesis, kōkua i ka hoʻolālā a me ka hoʻomohala ʻana i nā lāʻau peptide hou me nā hana pharmacological kūʻokoʻa.Ma ka hoʻokomo ʻana i nā kaʻina amino acid kikoʻī, hiki iā ia ke hoʻonui i ka therapeutic efficacy a hōʻemi i nā hopena ʻaoʻao o nā lāʻau lapaʻau.
L-Val-OH | DL-Val | HD-Val-OH | N-Me-L-Val-OH |
N-Me-L-Val.HCl | N-Me-D-Val | N-Me-D-Val-OH·HCl | N-Me-L-Val-Ome.HCl |
N-Me-D-Val-Ome.HCl | N-Me-Val-Obzl.HCl | N-Me-D-Val-Obzl.HCl | N-Me-Val-Obzl.Tos |
Boc-N-Me-Val-OH | Cbz-N-Me-D-Val-OH | Fmoc-N-Me-Val-OH | Fmoc-N-Me-DL-Val-OH |
Fmoc-N-Me-D-Val-OH | Cbz-N-Me-L-Val-OH |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.