NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Ola ola
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
ʻO ka peptide Synthesis:
Ma ke ʻano he amino acid i pale ʻia, ʻo Boc-N-Me-DL-Phe-OH ka mea pono loa i ka synthesis peptide solid-phase.ʻO ka pūʻulu pale tert-butoxycarbonyl (Boc) pale i ka pūʻulu amino i ka wā elongation kaulahao peptide, e pale ana i nā hopena ʻaoʻao makemake ʻole a me ka hōʻoia ʻana i ka hui kūpono o ke kaʻina peptide.Ma hope o ka synthesis, hiki ke hoʻoneʻe ʻia ka hui Boc ma lalo o nā kūlana kūpono, e hōʻike ana i ka pūʻulu amino manuahi no nā hoʻololi hou a i ʻole nā hopena.
Ka noiʻi biochemical:
Loaʻa ʻo Boc-N-Me-DL-Phe-OH i nā noi i nā noiʻi biochemical ma muli o kona hiki ke hoʻohui ʻia i loko o nā peptides me nā ʻano kikoʻī a me nā hale.Hiki ke hoʻohana ʻia no ka noiʻi ʻana i nā pilina o nā protein a i ʻole nā peptides me nā ligand kikoʻī, a me nā hana hana a me nā hoʻoponopono o kēia mau biomolecules i loko o nā ʻōnaehana biological.
ʻIke lāʻau lapaʻau:
Hana ʻo Boc-N-Me-DL-Phe-OH ma ke ʻano he waena i ka synthesis o nā lāʻau peptide therapeutically active.Hiki i nā hoʻololi e like me ka methylation ke hoʻololi i ka hana, kūpaʻa, a me nā waiwai pharmacokinetic o nā lāʻau peptide, e hoʻonui ana i kā lākou therapeutic efficacy.Hiki i kēia mau lāʻau peptide ke hōʻike i ka antibacterial, antiviral, anti-inflammatory, antitumor, a me nā hana ʻē aʻe, e hoʻolilo iā lākou i mea waiwai no ka mālama ʻana i nā maʻi like ʻole.
ʻEpekema Material:
Hiki ke hoʻohana ʻia ʻo Boc-N-Me-DL-Phe-OH i ka hoʻomākaukau ʻana i nā biomaterials me nā hana kikoʻī.No ka laʻana, hiki ke copolymerized me nā monomers ʻē aʻe e hana i nā mea polymer e hōʻike ana i ka biocompatibility a me ka bioactivity.Loaʻa kēia mau mea i nā noi i ka ʻenekinia kiko, ka lawe ʻana i ka lāʻau lapaʻau, biosensors, a me nā ʻano ʻē aʻe.
Boc-N-Me-L-Phe-OH | ZN-Me-L-Phe-OH | Fmoc-N-Me-L-Phe-OH | BOC-N-Me-D-Phe-OH |
FMOC-N-Me-D-Phe-OH | Boc-N-Me-L-Phe-OH.DCHA | Boc-DN-Me-Phe.DCHA | Fmoc-N-Me-D-Leu-OH |
N-Me-D-Phe | HN-Me-L-Phe-OH | HN-Me-L-Phe.Hcl |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.