NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Ola ola
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
ʻO HN-Me-L-Phe-HCl, i kapa ʻia ʻo N-methyl-L-phenylalanine hydrochloride, he mea waiwai nui me ka nui o nā noi i ka biochemistry, ka ʻike ʻana i ka lāʻau lapaʻau, peptide synthesis, a me ka ʻenekinia protein.
ʻO ka Peptide Synthesis a me ka ʻenekinia protein:
He mea koʻikoʻi ka HN-Me-L-Phe-HCl i ka peptide synthesis, ʻoi aku ka nui o ka hoʻokomo ʻana i kahi koena phenylalanine N-methylated.Ma muli o kāna ʻano kemika, hiki ke hoʻohui ʻia me nā waikawa amino ʻē aʻe e hana i nā peptides a i ʻole nā protein me nā ʻano kikoʻī a me nā hana.Hiki i kēia mau peptides a i ʻole nā protein ke loaʻa i ka mana therapeutic, e like me ka enzyme inhibitors, receptor antagonists, ulu ulu, a me nā mea hou aku.
ʻIke lāʻau lapaʻau:
Hana ʻo HN-Me-L-Phe-HCl ma ke ʻano he poloka hale koʻikoʻi no ka synthesizing peptides ikaika a me nā protein.Ma ka hoʻokomo ʻana iā ia i loko o nā kaʻina peptide, hiki ke hoʻohui ʻia nā peptides bioactive a i ʻole nā protein, hiki ke lilo i mau lāʻau lapaʻau hou a i ʻole nā mea mua.No ka laʻana, hiki ke hoʻohana ʻia i ka synthesis o nā peptides antimicrobial, nā peptides antiviral, nā peptides antitumor, a me nā molekole e pili ana i ka therapeutically.
Ka noiʻi biochemical:
I nā haʻawina biochemical, hiki ke hoʻohana ʻia ka HN-Me-L-Phe-HCl ma ke ʻano he reagent lepili no nā peptides a i ʻole nā protein.ʻO kona hoʻokomo ʻana i ke kaulahao peptide e hiki ai ke nānā pono a ʻike i ka ʻano peptide a i ʻole ka protein a me ka hana.He mea maikaʻi loa kēia i ke aʻo ʻana i ka pilina protein-protein, ka pelu ʻana i ka protein, ka paʻa o ka protein, a me nā ʻano ʻē aʻe o ka biochemistry protein.
Nā Agena Diagnostic and Biological Probes:
Hiki ke hoʻohana ʻia ʻo HN-Me-L-Phe-HCl i ka synthesis o nā mea noiʻi biological a me nā mea hana diagnostic.Ma muli o kona ʻano kemika kūikawā a me ka hoʻololi ʻana, hiki ke hoʻohana ʻia e lepili i nā biomolecules e like me nā antibodies, enzymes, a i ʻole nucleic acids no nā noi i ka maʻi maʻi, ke kiʻi biological, a i ʻole ka nānā ʻana i ka lāʻau.
Hoʻohui ʻia ʻo Chiral:
Ma ke ʻano he hui chiral, HN-Me-L-Phe-HCl ka hana koʻikoʻi i ka synthesis chiral.He mea koʻikoʻi ka hui ʻana o Chiral i ka ʻike ʻana i ka lāʻau lapaʻau ʻoiai ke hōʻike pinepine nei lākou i nā hana olaola kūʻokoʻa.Ma ka hoʻohana ʻana iā HN-Me-L-Phe-HCl ma ke ʻano he kumu chiral, hiki ke hoʻomalu ʻia ka chirality o nā peptides a i ʻole nā protein i ka wā synthesis, e alakaʻi ana i ka hana ʻana o nā huahana bioactive me nā hana i makemake ʻia.
HN-Me-L-Phe-OH | Boc-N-Me-DL-Phe-OH | N-Me-D-Phe | Boc-N-Me-L-Phe-OH |
ZN-Me-L-Phe-OH | Fmoc-N-Me-L-Phe-OH | BOC-N-Me-D-Phe-OH | FMOC-N-Me-D-Phe-OH |
Boc-N-Me-L-Phe-OH.DCHA | Boc-DN-Me-Phe.DCHA |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.