NUI
No nā nīnau e pili ana i kā mākou huahana a i ʻole ka papa inoa kumukūʻai, e ʻoluʻolu e waiho i kāu leka uila iā mākou a e hoʻopili mākou i loko o 24 mau hola.
NINAU ANOKūlana halihali
Hiki i ka wela maʻamau
Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai
Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
ola mālama
Ma kahi o 2 makahiki
Ka nui o ke kauoha liʻiliʻi:
1kg (kūkākūkā)
palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]D20
E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.
No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.
Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.
1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.
Peptide Synthesis: Ma keʻano he hale kūkulu i ka peptide synthesis, N-Me-D-Val-Obzl.HCl hiki i ka hoʻokomoʻana i nā kaʻina amino acid i loko o nā peptides.ʻO ka hoʻololi ʻana o ka methylation a me benzyloxycarbonylation e hoʻonui i ka paʻa a me ka solubility o ka amino acid i ka wā o ka synthesis, e hopena i nā peptides me ka maʻemaʻe kiʻekiʻe a me ka hana biological.
Noiʻi Biological: Hoʻohana ʻia ʻo N-Me-D-Val-Obzl.HCl i nā haʻawina olaola no ka noiʻi ʻana i ke kuleana o D-valine a me kāna mau derivatives i nā kaʻina kelepona a me nā hana olaola.Ma ka hoʻokomo ʻana i kēia pūhui i loko o nā peptides a i ʻole nā protein, hiki i nā mea noiʻi ke aʻo i kā lākou pilina me nā biomolecules ʻē aʻe, nā hana enzymatic, a me nā ala hōʻailona.
ʻIke a me ka hoʻomohala ʻana i ka lāʻau lapaʻau: ʻO nā hiʻohiʻona kū hoʻokahi o N-Me-D-Val-Obzl.HCl e lilo ia i moho waiwai no ka ʻike a me ka hoʻomohala ʻana i ka lāʻau.Ma ka hoʻokomo ʻana i kēia derivative amino acid i loko o nā moho lāʻau lapaʻau hou, hiki i nā mea noiʻi ke ʻimi i kona hopena therapeutic kūpono a loiloi i kona biocompatibility a me nā mea ʻona.
Proteomics and Protein Engineering: I ka proteomics and protein engineering, N-Me-D-Val-Obzl.HCl hiki ke hoʻohanaʻia e hoʻololi i nā proteins a iʻole nā peptides, e hoʻololi i ko lākou mau waiwai a iʻole nā hana.Hāʻawi kēia i ka hana ʻana i nā ʻano protein me ka hoʻomaikaʻi ʻana i ka paʻa, solubility, a i ʻole ka hana biological, e hiki ai ke ʻimi hou aku i ka hana protein a me ka hoʻolālā.
L-Val-OH | DL-Val | HD-Val-OH | N-Me-L-Val-OH |
N-Me-L-Val.HCl | N-Me-D-Val | N-Me-D-Val-OH·HCl | N-Me-L-Val-Ome.HCl |
N-Me-D-Val-Ome.HCl | Cbz-N-Me-D-Val-OH | N-Me-D-Val-Obzl.HCl | N-Me-Val-Obzl.Tos |
Boc-N-Me-Val-OH | Boc-N-Me-D-Val-OH | Fmoc-N-Me-Val-OH | Fmoc-N-Me-DL-Val-OH |
Fmoc-N-Me-D-Val-OH | Cbz-N-Me-L-Val-OH |
1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.