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15776-11-1 Met-NCA

15776-11-1 Met-NCA

ʻO ka wehewehe pōkole:

Ka nana aku ʻO ke keʻokeʻo a i ʻole keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline.
MF C6H9NO3S
MW 175.21
Maemae 98+


Huahana Huahana

ʻO ke kūlana kaʻaahi a me ke ʻano hoʻouna i ʻōlelo ʻia:
Ma ka lewa, ma ke kai a ma ke ala pololei

Kūlana mālama:
ʻO ka lewa inert, E mālama i loko o ka pahu hau, ma lalo o -20°C

Ka helu kauoha liʻiliʻi:
Kūkākūkā

palapala hōʻoia:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC loaʻa

D-Lys(tfa)-NCA (2)

Nā huaʻōlelo like

(S)-4-(2'-METHYLTHIOETHYL)OXAZOLIDINE-2,5-DIONE;

L-Met-NCA;

L-Methionine N-carboxyanhydride;

2,5-Oxazolidinedione, 4-[2-(methylthio)ethyl]-, (4S)-;

Hoʻopili i loko

Hoʻohana mau ʻia lākou no ka ʻeke pauda.A hiki iā lākou ke pale i ka lā a me ka wai mai ka pōʻino.

Hoʻopili i loko 2
Hoʻopili i loko 1
Hoʻopili i loko 3

kāʻei waho

Hiki i ka pahu paʻakikī ke pale i kāu huahana mai ka hāʻule a pulu.

Hoʻopili waho 3
Hoʻopili waho 2
Hoʻopili waho 1

Nā noi

ʻO ka Peptide Synthesis: Met-NCA he mea hoʻoikaika nui a hiki ke hoʻohana ʻia ma ke ʻano he hale kūkulu no ka peptide synthesis.Hoʻopili maikaʻi ʻo ia me nā amine e hana i nā paʻa peptide, hiki ke hana i nā peptides me nā ʻano kikoʻī a me nā waiwai.He mea maikaʻi loa kēia ʻano hana no ka synthesis o nā peptides biologically active i hiki ke hoʻohana ʻia i ka noiʻi lāʻau lapaʻau a i ʻole he therapeutics.

ʻIke a me ka hoʻomohala ʻana i ka lāʻau lapaʻau: ʻO ka Methionine kahi waikawa amino koʻikoʻi e pāʻani ana i nā kuleana koʻikoʻi i nā kaʻina olaola.Ma ka hoʻokomo ʻana i ka Met-NCA i loko o nā molekala lāʻau, hiki i nā mea noiʻi ke hoʻolauna i nā koena methionine e hiki ke hoʻonui i ka bioactivity, ka hiki ke huli, a i ʻole ke kūpaʻa o nā lāʻau.Hiki i kēia ala ke alakaʻi i ka loaʻa ʻana o nā lāʻau lapaʻau hou me ka hoʻomaikaʻi ʻana i nā profile pharmacological.

Nā noiʻi ʻepekema Material: Hiki ke hoʻohana ʻia ka Met-NCA i ka synthesis o nā polymers a me nā mea me nā hana methionine.Hiki i kēia mau mea ke hōʻike i nā waiwai kūʻokoʻa e like me ka biocompatibility, biodegradability, a i ʻole nā ​​pilina kikoʻī me nā ʻōnaehana olaola.Hiki ke hoʻohana ʻia i ka ʻenekinia kiko, ka lāʻau lapaʻau hou, a i ʻole ka hoʻomohala ʻana i nā biomaterials no nā noi olakino.

ʻO ka Bioconjugation a me ka Hoʻololi Protein: Hiki ke hoʻohana ʻia ʻo Met-NCA ma ke ʻano he reagent no nā hopena bioconjugation, e ʻae ana i ka hoʻopili ʻana o nā ʻano mole a i ʻole nā ​​hui hana i nā protein a i ʻole peptides.Hiki i kēia mana ke hoʻololi i nā protein me nā waiwai i makemake ʻia, e like me ka hoʻomaikaʻi ʻana i ka solubility, ke kūpaʻa, a i ʻole ka hiki ke huli.Hiki ke hoʻohana ʻia nā hopena bioconjugation e hoʻohana ana i ka Met-NCA i ka hoʻomohala ʻana i nā lāʻau lapaʻau e pili ana i ka protein, biosensors, a i ʻole nā ​​​​mea hana diagnostic.

Biochemical and Cellular Studies: ʻO ka hiki ke hoʻohui i nā peptides a me nā protein i loaʻa nā koena methionine me ka hoʻohana ʻana i ka Met-NCA e hāʻawi i kahi mea hana ikaika no ka noiʻi biochemical a me ke kelepona.Hiki i nā mea noiʻi ke hoʻohana i kēia mau moleke e noiʻi i ka pilina protein-protein, enzyme kinetics, a i ʻole nā ​​ala hōʻailona kelepona.Hiki ke hoʻohana ʻia nā peptides met-NCA ma ke ʻano he probes a i ʻole inhibitors e aʻo ai i nā kaʻina hana olaola a me nā mīkini maʻi.

huahana pili

L-Lys(Boc) Boc-Lys(Cbz)-Ol Z-Lys(boc)-Ala-Ala-OBzl Fmoc-L-Lys(Fmoc)-OH
Lys(Fmoc)-OH Boc-Lys(AC) L-Lys-oet.2HCl Fmoc-D-Lys(Boc)-OH
L-Lys(Cbz)-OH Boc-L-Lys(Cbz)-OH D-Lys-Ome.2Hcl Fmoc-L-Lys(Boc)-OH
D-Lys(cbz)-OH Boc-L-Lys(Boc)-OSu HL-Lys(cbz)-OBzl•HCl Fmoc-L-Lys-OH·HCl
H-Lys(Ac)-OH Boc-L-Lys(Boc)-OH·DCHA L-Lys(cbz)-Ome.Hcl Fmoc-Lys-Ome·HCl
Lys(tfa)-OH Boc-D-Lys(Boc)-OH lys(Cbz)-Otbu.HCl Fmoc-D-Lys-OH·HCl
D-Lys(tfa)-OH Boc-L-Lys(Cbz)-OMe D-Lys(Cbz)-OtBu.HCl Cbz-Lys(tfa)-OH
D-Lys(tfa)-NCA Boc-D-Lys(Cbz)-OH L-Lys.2Hcl Cbz-lys(cbz)-osu
L-Lys(tfa)-NCA Boc-L-Lys(Cbz)-OH·DCHA L-Lys-Ome.2Hcl Cbz-L-Lys(Cbz).DCHA
Lys(Cbz)-NCA Boc-L-Lys(Fmoc)-OH H-Lys-Lys.3HCl Cbz-L-Lys-OH
D-Lys(Cbz)-NCA Fmoc-L-Lys(tfa)-OH lys-obzl.2hcl Cbz-L-Lys(Cbz)-OH
ZL-Lys(Boc).DCHA Fmoc-L-Lys(DDC) D-Lys(Fmoc).HCl Cbz-Lys(AC)-OH
Ac-Lys-OH Fmoc-D-Lys(Cbz)-OH Lys(Fmoc).HCl Cbz-Lys(BOC)-ome
AC-Lys(Boc)-NH2 Fmoc-D-Lys(Fmoc)-OH D-Lys.Hcl Cbz-Lys(Boc)-Otbu
AC-Lys(Boc)-OH Fmoc-L-Lys(Cbz) D,L-Lys.Hcl Cbz-L-Lys(BOC)-OH
H-Lys(Cbz)-OtBu Fmoc-L-Lys(AC) L-Lys.HCl Cbz-L-Lys(Fmoc)-OH
Boc-Lys(Cbz).DCHA Cbz-L-Lys-Ome.Hcl Boc-L-Lys-OH Cbz-L-Lys-obzl.Hcl
Boc-Lys(tfa)-OH Z-DL-Lys(cbz)-OH    

Kiekie

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