ʻO ka Peptide Synthesis: Met-NCA he mea hoʻoikaika nui a hiki ke hoʻohana ʻia ma ke ʻano he hale kūkulu no ka peptide synthesis.Hoʻopili maikaʻi ʻo ia me nā amine e hana i nā paʻa peptide, hiki ke hana i nā peptides me nā ʻano kikoʻī a me nā waiwai.He mea maikaʻi loa kēia ʻano hana no ka synthesis o nā peptides biologically active i hiki ke hoʻohana ʻia i ka noiʻi lāʻau lapaʻau a i ʻole he therapeutics.
ʻIke a me ka hoʻomohala ʻana i ka lāʻau lapaʻau: ʻO ka Methionine kahi waikawa amino koʻikoʻi e pāʻani ana i nā kuleana koʻikoʻi i nā kaʻina olaola.Ma ka hoʻokomo ʻana i ka Met-NCA i loko o nā molekala lāʻau, hiki i nā mea noiʻi ke hoʻolauna i nā koena methionine e hiki ke hoʻonui i ka bioactivity, ka hiki ke huli, a i ʻole ke kūpaʻa o nā lāʻau.Hiki i kēia ala ke alakaʻi i ka loaʻa ʻana o nā lāʻau lapaʻau hou me ka hoʻomaikaʻi ʻana i nā profile pharmacological.
Nā noiʻi ʻepekema Material: Hiki ke hoʻohana ʻia ka Met-NCA i ka synthesis o nā polymers a me nā mea me nā hana methionine.Hiki i kēia mau mea ke hōʻike i nā waiwai kūʻokoʻa e like me ka biocompatibility, biodegradability, a i ʻole nā pilina kikoʻī me nā ʻōnaehana olaola.Hiki ke hoʻohana ʻia i ka ʻenekinia kiko, ka lāʻau lapaʻau hou, a i ʻole ka hoʻomohala ʻana i nā biomaterials no nā noi olakino.
ʻO ka Bioconjugation a me ka Hoʻololi Protein: Hiki ke hoʻohana ʻia ʻo Met-NCA ma ke ʻano he reagent no nā hopena bioconjugation, e ʻae ana i ka hoʻopili ʻana o nā ʻano mole a i ʻole nā hui hana i nā protein a i ʻole peptides.Hiki i kēia mana ke hoʻololi i nā protein me nā waiwai i makemake ʻia, e like me ka hoʻomaikaʻi ʻana i ka solubility, ke kūpaʻa, a i ʻole ka hiki ke huli.Hiki ke hoʻohana ʻia nā hopena bioconjugation e hoʻohana ana i ka Met-NCA i ka hoʻomohala ʻana i nā lāʻau lapaʻau e pili ana i ka protein, biosensors, a i ʻole nā mea hana diagnostic.
Biochemical and Cellular Studies: ʻO ka hiki ke hoʻohui i nā peptides a me nā protein i loaʻa nā koena methionine me ka hoʻohana ʻana i ka Met-NCA e hāʻawi i kahi mea hana ikaika no ka noiʻi biochemical a me ke kelepona.Hiki i nā mea noiʻi ke hoʻohana i kēia mau moleke e noiʻi i ka pilina protein-protein, enzyme kinetics, a i ʻole nā ala hōʻailona kelepona.Hiki ke hoʻohana ʻia nā peptides met-NCA ma ke ʻano he probes a i ʻole inhibitors e aʻo ai i nā kaʻina hana olaola a me nā mīkini maʻi.