Kina Boc-His(Boc)-Aib-OH Mea Hana a Hale Hana |Jiayinglai

Boc-His(Boc)-Aib-OH

ʻO ka wehewehe pōkole:

Ka nana aku	ʻO ka pauka keʻokeʻo keʻokeʻo
MF
MW
Maemae	98+

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Kūlana halihali
Hiki i ka wela maʻamau

Manaʻo i ke ʻano hoʻouna
Ma ka lewa Ma ka aina Ma ke kai

Kūlana mālama:
E mālama i kahi pōʻeleʻele, Inert ea, lumi wela

ola mālama
Ma kahi o 2 makahiki

Ka nui o ke kauoha liʻiliʻi:
1kg （kūkākūkā）

palapala hōʻoia:COA, wahi hehee, Hoʻololi kikoʻī [α]_D²⁰

E hoʻouna mākou i nā ʻikepili āu e makemake ai.Hiki iā ʻoe ke ʻike i ka ʻikepili ma mua ma ke ʻano he kuhikuhi.

No nā huahana maʻamau, hoʻouna mākou i ka ʻikepili hou ma hope o ka puka ʻana mai.

Nā huaʻōlelo like

Boc-His(Boc)-Aib-OH

Hoʻopili i loko

Hoʻohana pinepine ʻia lākou no ka hoʻopili ʻana i ka pauka.Pili ia i nā koi o nā mea kūʻai aku.No laila, e haʻi mai iā mākou i kāu koi ma mua o ka hoʻopaʻa ʻana inā loaʻa iā ʻoe nā noi kūikawā.

kāʻei waho

1kg a 25kg He paʻakikī ka paʻi waho.A he mea paʻakikī ke ʻoki a hōʻino.Hiki iā ia ke pale pono i kāu mau huahana.

Nā noi

ʻO ka Peptide Synthesis a me ka Hoʻololi: Hiki iā Boc-His (Boc) -Aib-OH ke lilo i hale kūkulu hale i loko o kahi kaulahao peptide, hiki ke hana i nā peptides me nā kaʻina kikoʻī a me nā hana ma o ka ligation me nā amino acids a i ʻole nā ʻāpana peptide.Loaʻa i kēia mau peptides i hoʻohui ʻia maʻamau i nā noi nui i ka ʻike ʻana i ka lāʻau lapaʻau, ka noiʻi biochemical, a me nā wahi e pili ana.
Hāʻawi ʻia i ka loaʻa ʻana o ka histidine (His) a me ka α-aminoisobutyric acid (Aib), nā waiwai kūʻokoʻa o kēia mau amino acids e hāʻawi iā Boc-His (Boc)-Aib-OH me kahi kuleana koʻikoʻi i kekahi mau kaʻina peptide.Hiki iā lākou ke hoʻonui i ka paʻa a me ka hana olaola o nā peptides.
Noiʻi a me ka hoʻoponopono ʻana i nā haʻawina olaola: Loaʻa iā Boc-His(Boc)-Aib-OH ka hana koʻikoʻi maoli, e lilo ia i mea hana waiwai no nā haʻawina ʻoihana olaola.Hiki i nā mea noiʻi ke hoʻokomo iā ia i loko o nā ʻōnaehana olaola e nānā i kona hopena i nā kaʻina cellular, a laila e loaʻa ai ka ʻike hohonu i nā mīkini physiological a me nā pathological.
Ma ka hana ʻana i ka pūʻulu imidazole o histidine a me ke ʻano kūʻokoʻa o ka α-aminoisobutyric acid, hiki i ka Boc-His(Boc)-Aib-OH ke hoʻololi i kāna mau pilina me nā mea loaʻa a i ʻole nā biomolecules ʻē aʻe, e hoʻoponopono ana i nā pane kūlohelohe kikoʻī a i ʻole nā ala transduction hōʻailona.
Hoʻolālā a me ka hoʻomohala ʻana i ka lāʻau lapaʻau: Loaʻa iā Boc-His(Boc)-Aib-OH ka waiwai hoʻohana pono i ka ʻike o ka lāʻau.Hiki i ka hoʻololi ʻana a i ʻole ka hoʻoponopono ʻana ke alakaʻi i nā pūhui me nā hana pharmacological kikoʻī, e lawelawe ana ma ke ʻano he lāʻau moho no ka hoʻokolokolo hou a me ka hoʻomohala ʻana.
Ke noʻonoʻo nei i nā waiwai chelating metala o ka hui imidazole o histidine a me ka biocompatibility o ka α-aminoisobutyric acid, hiki ke hoʻolālā ʻia ʻo Boc-His(Boc)-Aib-OH no ka hoʻomohala ʻana i ka lāʻau hou e kuhikuhi ana i nā maʻi kūikawā a i ʻole nā kumu olaola.
Biochemical and Biophysical Research: Hiki iā Boc-His(Boc)-Aib-OH ke lilo i kumu hoʻohālike no ke aʻo ʻana i nā ʻano hana pilina ma waena o nā peptides a me nā biomolecules e like me nā protein a me DNA, a me ka peptide folding a me ke kūpaʻa i loko o nā ʻōnaehana olaola.

Ma o ka noiʻi ʻana i kāna mau pilina me nā biomolecules like ʻole, hiki ke loaʻa kahi ʻike hohonu o nā waiwai biochemical a me nā hana o nā peptides.

huahana pili

L-Kona-OH	HD-His-OH	H-Kona(trt)-OH	Boc-L-His(Boc)-OH.Dcha
Boc-His(Boc)-OH	Boc-D-His(Boc)-OH	Fmoc-D-His(Fmoc)-OH	FMOC-Kona(BOC)-OH
Boc-L-His(Trt)-Aib-OH

No ke aha e koho ai iā mākou

1. No ka MOQ: Hiki iā mākou ke hoʻololi e like me kāu koi.
2. E pili ana i ka hāpana: Pono ka hāpana i ka uku hōʻailona, hiki ke lawe i ka ukana e hōʻiliʻili aiʻole hiki iāʻoe ke uku iā mākou ma mua.
3. Mold workshop, hiki ke hoʻopilikino ʻia e like me ka helu o nā hiʻohiʻona.
4. Hāʻawi mākou i ka lawelawe maikaʻi loa.Ke hana nei kekahi hui kūʻai akamai iā ʻoe.
5. E pili ana i ka hoʻololi: E ʻoluʻolu e leka uila a kamaʻilio mai iaʻu ma kou ʻoluʻolu.

Mua: 7360-23-8 Cbz-Pro-Pro-OH

Aʻe: 15776-11-1 Met-NCA

E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou