, Kina 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE Mea hana a hale hana |Jiayinglai
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87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

ʻO ka wehewehe pōkole:

Ka nana aku ʻO ke keʻokeʻo a i ʻole keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline.
MF C21H22N2O5
MW 382.41
Maemae 98+


Huahana Huahana

ʻO ke kūlana kaʻaahi a me ke ʻano hoʻouna i ʻōlelo ʻia:
?

Kūlana mālama:
Hoʻopaʻa ʻia i kahi maloʻo, 2-8 ° C

Ka nui o ke kauoha liʻiliʻi:
Kūkākūkā

palapala hōʻoia:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC loaʻa

D-Lys(tfa)-NCA (2)

Nā huaʻōlelo like

FMOC-ALA-ALA-OH;
Fmoc-L-Ala-L-Ala-OH;
(S)-2-((S)-2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanamido)propanoic acid;
Fmoc-Ala-Ala-OH99%;
FMoc-Ala-Ala;
FMOC-ALA-ALA-OH;
FMOC-L-ALANYL-L-ALANINE;
FMoc-AA-OH;
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine

Hoʻopili i loko

Hoʻohana mau ʻia lākou no ka ʻeke pauda.A hiki iā lākou ke pale i ka lā a me ka wai mai ka pōʻino.

kāʻei waho

Hiki i ka pahu paʻakikī ke pale i kāu huahana mai ka hāʻule a pulu.

Nā noi

ʻO kēia huahana he polypeptide i haku ʻia me 28 amino acids.No ka N - acetyl - L - siliki ammonia acyl - L - alpha amino ammonia acyl - L - propylene ammonia acyl - L - propylene ammonia acyl - L - valerian ammonia acyl - L - alpha amino ammonia acyl - L - Sue ammonia acyl - L - uea ammonia acyl - L - uea ammonia acyl - L - alpha glutamine - L - ʻokoʻa māmā ammonia acyl - L - Sue ammonia acyl - L - Sue ammonia acyl - L - lai ammonia acyl - L - alpha amino ammonia acyl - L - ʻO ka ammonia acyl kukui - L - lai ammonia acyl - L - alpha - glutamine - L - lai ammonia acyl - L - lai ammonia acyl - L - alpha glutamine - L - valerian ammonia acyl - L - valerian ammonia acyl - L - alpha glutamine - L - alpha - glutamine - L - propylene ammonia waina - L - alpha - glutamine - L - asparagine.E like me ka helu ʻana o ka waiwai anhydrous a me ka acetic acid-free, ʻo ke ʻano o ka thymus (C129 H215 N33O55) he 95.0% ~ 105.0%.
ʻO kēia huahana he pauka keʻokeʻo a keʻokeʻo paha a i ʻole ka nuipaʻa.
Hoʻoheheʻe ʻia kēia huahana i ka waikawa trifluoroacetic, hiki ke hoʻoheheʻe ʻia i ka wai, hiki ʻole ke hoʻoheheʻe ʻia i ka acetonitrile, ether a me trichloromethane.
E lawe i kēia huahana, e kaupaona pololei, e hoʻohui i ka 0.02mol/L phosphate buffer solution (pH 7.0) (e lawe i 2.72g potassium dihydrogen phosphate, e hoʻohui i ka 0.1mol/L sodium hydroxide solution 116.4ml e hoʻoheheʻe, e hoʻoheheʻe me ka wai i 1000ml) a hana i kahi. ʻO ka hopena i loaʻa ma kahi o 5mg i kēlā me kēia 1ml.Hoʻoholo ʻia e like me ke kānāwai (Appendix ⅥE o ka Māhele II o Pharmacopoeia, 2010 edition), pono ka curl kikoʻī -100.0 ° a -110.0 ° ma muli o ka helu ʻana o nā mea anhydrous a me ka acetic acid-free.
ʻAʻole i wehewehe piha ʻia ke ʻano o ka hana o kēia huahana i ka mālama ʻana i ka maʻi hepatitis B a me ka hoʻonui ʻana i ka ʻōnaehana pale.Ua hōʻike ʻia ka nui o nā hoʻokolohua in vitro hiki i kēia huahana ke hoʻoikaika i ka maturation o T lymphocytes ma o ka hoʻoulu ʻana i ka mitogen o nā lymphocytes koko peripheral, hoʻonui i nā pae o interferon α, interferon γ, interleukin 2, interleukin 3 a me nā mea lymphatic ʻē aʻe i huna ʻia e nā cell T. ma hope o ka hoʻoulu ʻana o ka antigen a i ʻole mitogen, a i ka manawa like e hoʻonui ai i ke kiʻekiʻe o nā mea hoʻokipa lymphofactor ma ka ʻili o nā cell T.Hiki iā ia ke hoʻonui i ka pane o allogeneic a me autologous kanaka i hui pū ʻia nā lymphocytes ma o ka hoʻāla ʻana o nā cell CD4.Hiki i kēia huahana ke hoʻonui i ka hōʻuluʻulu o nā cell pre-NK, a hiki i ka interferon ke hoʻonui i ko lākou cytotoxicity.Ua hōʻike ʻia nā hoʻokolohua in vivo hiki i kēia huahana ke hoʻonui i ka pae hōʻike o ka interleukin-2 receptor a me ka pae huna o interleukin-2 i loko o nā lymphocytes ʻiole ma hope o ka hoʻoulu ʻana o cancanadin A.

huahana pili

Gly-Ala-Ome.hcl Fmoc-L-Ala-OH β-Ala-Ome.HCl L-Ala-Phe-OH
Gly-Gly-Ala-Ome.hcl Fmoc-DL-Ala HL-Ala-Ome.Hcl L-Ala-Leu-OH
L-ALa Fmoc-D-Ala-OH β-Ala-Otbu.HCl L-Ala-Pro-OH
DL-ALA Fmoc-β-Ala-OH DL-Ala-Otbu.Hcl DL-Ala-DL-Val
H-Ala-ol Fmoc-LN-Me-Ala-OH L-Ala-NH2.HCl Ala-Gly-Ome.hcl
β-Ala-ol Fmoc-N-Me-D-Ala-OH HD-Ala-NH2·HCl L-Ala-Ala-Obzl.HCl
D-ALa Fmoc-Ala-Cl HD-Ala-NH2 D-Ala-D-Ala-Ome.Hcl
H-β-Ala-OH Fmoc-L-Ala-Ol Ac-L-Ala-NH2 H-Ala-Ala-Otbu.HCL
HN-Me-L-Ala-OH fmoc-β-Ala-NH2 Ac-D-Ala-NH2 Boc-Ala-Phe-OH
HN-Me-D-Ala-OH Fmoc-Ala-Ome AC-D,L-Ala-OH Boc-L-Ala-Leu
L-Ala-NCA Fmoc-Ala-Osu Ac-D-Ala-OH Boc-ALa-Val-OH
D-Ala-NCA fmoc-β-Ala-osu AC-L-Ala-OH Boc-Ala-Pro
L-Ala-nbu.hcl Cbz-L-Ala-OH AC-L-Ala-OME Boc-Ala-Gly-OH
L-Ala-Otbu Cbz-D-Ala-OH Pht-D-Ala Boc-Ala-Ala-OH
D-ALa-Oipr.HCL Cbz-N-Me-L-Ala-OH Pht-L-Ala Boc-Ala-Ala-Ome
D-Ala-Otbu.Hcl Cbz-N-Me-D-Ala-OH Boc-L-Ala-OH Boc-Ala-Ala-Obzl
N-Me-L-Ala-OMe Cbz-DL-Ala-OH Boc-D-Ala-OH Fmoc-Ala-pro
HD-Ala-OBzl·HCl Z-β-L-Ala-OH Boc-DL-Ala-OH Fmoc-Ala-gly-OH
β-Ala-Obzl.Tos Cbz-L-Ala-OL Boc-β-Ala-OH Fmoc-L-Ala-Ala-OH
H-Ala-OBzl·HCl Cbz-L-Ala-NH2 Boc-N-Me-Ala-OH Fmoc-β-Ala-D-phe
HL-Ala-OBzl.Tos-OH Cbz-L-Ala-Ome Boc-N-Me-DL-Ala-OH Fmoc-β-Ala-D-Tyr(Et)
HD-Ala-Oet.HCl Cbz-D-Ala-OMe Boc-N-Me-D-Ala-OH Cbz-Ala-Val-OH
HL-ALa-Oipr.HCL Cbz-Beta-Ala-Ome Boc-L-Ala-Ol Cbz-L-Ala-Ala-OH
N-Me-Ala-Otbu.Hcl Cbz-β-Ala-Otbu Boc-D-Ala-Ol Cbz-Ala-Pro-OH
HL-Ala-OtBu·HCl Cbz-L-Ala-Osu Boc-DL-Ala-Ol Cbz-L-Ala-Leu-OH
H-DL-Ala-OMe.HCl Cbz-Beta-Ala-OSU Boc-Ala-NH2 Cbz-L-Ala-Ala-Ome
β-Ala-Oet.HCl Ala-Ala-OH Boc-D-Ala-NH2 Ala-Ala-Ome.HCL
N-Me-L-Ala-Ome.hcl Ala-gly Boc-β-Ala-NH2 Val-Ala
HD-Ala-Ome.Hcl L-ALa-Val-OH Boc-D-4-Chloropheny(alanine) Boc-Ala-Pro
Boc-L-ALA-OBZL Boc-Leu-Ala Boc-D-3(1-Naphthgl)-alanine Boc-Val-Ala
Boc-L-Ala-OSu Fmoc-leu-ala Boc-L-Ala-Ome Cbz-Val-Ala-OH
Boc-L-Beta-Ala-Osu Cbz-Leu-Ala-OH Boc-D-Ala-OMe Cbz-Val-Ala-Ome
Boc-D-Ala-OSu Phe-Ala Boc-L-Ala-Otbu Leu-Ala-OH
Fmoc-L-Ala-OH.H2O Boc-Phe-Ala-OH Z-Lys(boc)-Ala-Ala-OBzl HL-Thr-OBzl·oxalate
HL-Thr(Bzl)-OBzl.oxalate Cbz-Phe-Ala-OH  

Kiekie

1. Loaʻa ka lawelawe R&D
2. ʻO ka mea hana i hōʻoia ʻia ʻo ISO, hōʻoia maikaʻi
3.A piha piha o ka lawelawe ukali i ka wā hana
4.High kumu kūʻai pono
Nā palapala hōʻoia 5.Quality i hāʻawiʻia no ka noi a ka mea kūʻai
6.Great ma hope o ke kūʻai aku, mālama i ka pilina pili me ka mea kūʻai
7.Full punawai e kōkua i ka ho'ēmiʻana i ke kumukūʻai moku
8.Free hāpana hāʻawi ʻia e nānā i ka maikaʻi ma mua o kekahi uku
9.Payment manawa kūkākūkā
10.Assit nā mea kūʻai aku e pili ana i nā hihia ma Kina


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