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Nā ʻano pale amino maʻamau

Nā ʻano pale amino maʻamau

1. Cbz
ʻO Benzyloxycarbonyl (Cbz) Amino Palekana
Hoʻopau i ka N-benzyloxycarbonyl (Cbz)
Hoʻohana mau ʻia nā reagents - CbzCl

2. Alloc
ʻO Allyloxycarbonyl (Alloc) pūʻulu amino pale

3. Trifluoroacetyl
ʻO ka hui amino palekana Trifluoroacetyl

4. Benzila
p-methoxybenzyl (PMB) pūʻulu amino pale
2,4-dimethoxybenzyl pūʻulu amino pale
Benzyl pale amino
Hoʻopau i ka hui amino pale benzyl
N-Bn debenzylation ma ke ʻano chloroformate

5. Pht (phthaloyl)
ʻO nā pūʻulu amino palekana ʻo Phthaloyl (Pht).
Hoʻopau i ka pūʻulu amino pale phthaloyl

6. Benzenesulfonyl
ʻO ka hui amino mālama ʻia ʻo Nitrobenzenesulfonyl
p-toluenesulfonyl (Tos) amino pale

7. Trt
ʻO ka amino mālama ʻia ʻo Trityl
Hoʻopau i ka hui amino palekana trityl

8. Boc
ʻO ka hui amino pale ʻia ʻo Tert-butoxycarbonyl
Hoʻopau i ka N-tert-butoxycarbonyl
Oxalyl Chloride De-Boc

9. Fmoc
Wat methoxycarbonyl protected amino pūʻulu
Hoʻohana maʻamau - Fmoc-Cl

10. SEM
ʻO amino palekana SEM

11. ʻO nā mea ʻē aʻe
ʻO ka hui amino pale ʻia ʻo Acetamide
ʻO Clauson-Kaas pyrrole synthesis reaction (hiki ke hoʻohana ʻia kēia hopena ma ke ʻano he ala e pale ai i nā hui amino, hiki ke pani i ka pale Boc pālua, a ʻoi aku ka paʻa)
Hoʻohana pinepine ʻia nā reagents - benzyl (chloromethyl) ether
Hoʻohana maʻamau - (chloromethyl) methyl ether [MOMCl]
Palekana Carbamate


Ka manawa hoʻouna: Sep-07-2023